Gleen loses his younger brother, who is killed because of Pong’s gambling affairs, by a man Pong had cheated. Gleen forgives Pong about that but one day the same cheated man who killed his brother takes Muang hostage, a girl he once saved from a gang raping. As the man wants to exchange Muang with Pong, Gleen learns that Pong used his brother as a shield as he wanted to escape. Tag Team Hearts illustrates the intrigues that can be associated with friendship.